Glucose-6-Phosphate Assay (F), Catalog: MA-0289

Catalog MA-0289

Size 100 wells

Sample Type  Cell & Tissue Lysates, Urine, Plasma, Serum, Other biological fluids

Method of Detection Fluorometric, Ex/Em = 535/587 nm

Assay Type  Quantitative

Application A plate-based simple, sensitive fluorometric assay to measure Glucose-6-Phosphate in a variety of sample types.

Sensitivity < 10 picomole range

Storage Conditions -20°C

Shipping Temperature Gel Pack

Shelf Life One year from the date of delivery

Glucose-6-phosphate (G6P) is an important metabolic intermediate, linking several major metabolic pathways, essential for glucose homeostasis and overall cellular function. G6P is the first intermediate in glycolysis leading to ATP production. It is the starting point for the pentose phosphate pathway, generating NADPH and ribose-5-phosphate. G6P can be converted to G1P leading to glycogen synthesis for storage. G6P is dephosphorylated to glucose for transport through the body, converted to fatty acids through de novo lipogenesis or used in the hexosamine pathway, leading to protein glycosylation. As a regulatory molecule,, G6P affects glycogen phosphorylase, controlling the rate of glycogen breakdown. Dysregulation contributes to type 2 diabetes, glycogen storage diseases and cancer. AkrivisBio’s Glucose-6-Phosphate Assay is a simple, very sensitive way to measure G6P with a sensitivity in the very low (< 10) picomole range.