Caspase-3 Activity Assay, Catalog: MA-0191

US$395.00

25, 100 and 200 wells, Colorimetric, OD 405 nm 

PRODUCT SUMMARY

Catalog MA-0191

Size 25, 100 or 200 wells

Sample Type Cell Lysates, Tissue Lysates

Method of Detection Colorimetric, OD 405 nm 

Assay Type Quantitative

Application A plate based simple, sensitive colorimetric assay to monitor Caspase 3 activity and any changes that can occur under different cellular stresses.

Sensitivity 1 mU/well

Storage Conditions -20°C

Shipping Temperature Gel Pack

Shelf Life One year from the date of delivery

DESCRIPTION

Caspase-3 initiates apoptosis after being activated in response to various intrinsic and extrinsic signals. It degrades specific proteins involved in DNA repair, cytoskeletal maintenance, and cell cycle progression, ensuring a systematic, orderly breakdown of the cell and preventing the release of potentially harmful cellular components into the surrounding environment. This results in characteristic morphological changes associated with apoptosis including cell shrinkage, chromatin condensation and formation of apoptotic bodies. AkrivisBio’s Caspase 3 Activity Assay is a simple sensitive means of monitoring Caspase 3 activity and any changes which can occur under different cellular stresses.