TG100-115, Catalog: B1667

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TG100-115, TG100 115; TG100115; 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol

PRODUCT SUMMARY

Alternate Names TG100-115, TG100 115; TG100115; 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol

Appearance Solid

CAS # 677297-51-7

Molecular Formula C₁₈H₁₄N₆O₂

Molecular Weight 346.34 

Purity > 98%

Solubility DMSO

SMILES C1=CC(=CC(=C1)O)C2=NC3=C(N=C2C4=CC(=CC=C4)O)N=C(N=C3N)N

InChi InChI=1S/C18H14N6O2/c19-16-15-17(24-18(20)23-16)22-14(10-4-2-6-12(26)8-10)13(21-15)9-3-1-5-11(25)7-9/h1-8,25-26H,(H4,19,20,22,23,24)

InChi Key UJIAQDJKSXQLIT-UHFFFAOYSA-N

PubChem CID 10427712

MDL Number MFCD16038873

Storage Conditions -20°C

Shipping Conditions Gel Pack

USAGE For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

DESCRIPTION

TG100-115 is a PI3K γ and -δ inhibitor (IC50 = 83 and 235 nM, respectively).