Pinacidil monohydrate, Catalog: B1904

Alternate Name (±)-N-Cyano-N′-4-pyridinyl-N″-(1,2,2-trimethylpropyl)guanidine monohydrate

Appearance White solid

CAS # 85371-64-8

Molecular Formula C₁₃H₁₉N_5.H₂O

Molecular Weight 263.34

Purity ≥ 98% by HPLC

Solubility DMSO (~ 15 mg/ml)

SMILES CC(C(C)(C)C)N=C(NC#N)NC1=CC=NC=C1.O

InChi InChI=1S/C13H19N5.H2O/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11;/h5-8,10H,1-4H3,(H2,15,16,17,18);1H2

InChi Key AFJCNBBHEVLGCZ-UHFFFAOYSA-N

PubChem CID 55329

MDL Number MFCD00242745

Storage Conditions -20°C

Shipping Conditions Gel Pack

USAGE For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

Pinacidil is a cyanoguanidine compound that acts as a potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively. Induces relaxation of serotonin-produced contractions in porcine and human arterial rings. Vasodilator. Antihypertensive agent.