ML-354, Catalog: 9415

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1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol

PRODUCT SUMMARY

Alternate Names 1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol

Appearance Yellow solid

CAS # 89159-60-4

Molecular Formula C₁₆H₁₄N2O₃

Molecular Weight 282.39

Purity ≥ 98% by HPLC

Solubility DMSO (~25 mg/ml)

SMILES CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=C1CO)C3=CC=CC=C3

InChi InChI=1S/C16H14N2O3/c1-17-14-8-7-12(18(20)21)9-13(14)16(15(17)10-19)11-5-3-2-4-6-11/h2-9,19H,10H2,1H3

InChi Key GNJUKVGDCUKDLF-UHFFFAOYSA-N

PubChem CID 752812

Storage Conditions -20°C

Shipping Conditions Gel Pack

USAGE For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air, light and moisture.

DESCRIPTION

ML-354 is a selective PAR4 antagonist (IC₅₀ = 140 nM). Displays 71-fold selectivity for PAR4 over PAR1 (PAR-1 IC₅₀ = 10 μM).