PHT-427, Catalog: 2465

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4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide

PRODUCT SUMMARY

Alternate Name 4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide

Appearance White to off-white solid

CAS # 1191951-57-1

Molecular Formula C₂₀H₃₁N₃O₃S₂

Molecular Weight 409.61

Purity ≥ 98% by HPLC

Solubility DMSO (> 80 mg/ml)

SMILES CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2

InChi InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)

InChi Key BYWWNRBKPCPJMG-UHFFFAOYSA-N

PubChem CID 44240850

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

DESCRIPTION

A potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor. PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity.