GSK-2801, Catalog: 9553
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4-(5-methyl-4-(tosylmethyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide
4-(5-methyl-4-(tosylmethyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide
Alternate Names 4-(5-methyl-4-(tosylmethyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide
Appearance Off-white solid
CAS # 1619994-68-1
Molecular Formula C₂₀H₂₁NO₄S
Molecular Weight 371.54
Purity ≥ 98% by HPLC
Solubility DMSO (~10 mg/ml)
SMILES CC(C1=CC(C2=CC=CC=C2S(=O)(C)=O)=C3C=C(OCCC)C=CN13)=O
InChi InChI=1S/C20H21NO4S/c1-4-11-25-15-9-10-21-18(14(2)22)13-17(19(21)12-15)16-7-5-6-8-20(16)26(3,23)24/h5-10,12-13H,4,11H2,1-3H3
InChi Key KHWCPNJRJCNVRI-UHFFFAOYSA-N
MDL Number MFCD26142953
Storage Conditions -20°C
Shipping Conditions Gel Pack
Usage For Research Use Only! Not For Use in Humans.
Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.
GSK-2801 is a potent, selective, and cell-permeable inhibitor of the BAZ2 family of bromodomain containing proteins. GSK-2801 binds to BAZ2 bromodomains with dissociation constants (KD) of 136 and 257 nM for BAZ2B and BAZ2A, respectively.