EUK-118, Catalog: 2173

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(acetato-κO)[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[3,5-dimethoxyphenolato-κO]](2-)]-manganese

PRODUCT SUMMARY

Alternate Names (acetato-κO)[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[3,5-dimethoxyphenolato-κO]](2-)]-manganese

Appearance Off-white solid

CAS # 186299-34-3

Molecular Formula C₂₂H₂₅MnN₂O₈

Molecular Weight 500.38

Purity ≥ 95%

Solubility DMSO (~ 20 mg/ml)

SMILES CC(=O)[O-][Mn]123([N+](=Cc4c(cc(cc4OC)OC)[O-]1)CC[N+]2=Cc5c(cc(cc5OC)OC)[O-]3)[Mn][Mn+]

InChi InChI=1S/C20H24N2O6.C2H4O2.3Mn/c1-25-13-7-17(23)15(19(9-13)27-3)11-21-5-6-22-12-16-18(24)8-14(26-2)10-20(16)28-4;1-2(3)4;;;/h7-12,23-24H,5-6H2,1-4H3;1H3,(H,3,4);;;/q;;;+1;+2/p-3/b21-11+,22-12+;;;;

InChi Key NKZPUKNJLPQHHM-CAGONKBASA-K

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

DESCRIPTION

A structural analog of EUK 8 and EUK 134 with significantly reduced activity. Acts as a synthetic catalytic scavenger of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity. Superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity) was inhibited by EUK 118 with an IC₅₀ value of 2.0 µm