OG-L002, Catalog: 9406

Alternate Names 4'-((1S,2R)-2-aminocyclopropyl)-[1,1'-biphenyl]-3-ol

Appearance White solid

CAS # 1357302-64-7

Molecular Formula C₁₅H₁₅NO

Molecular Weight 225.29

Purity ≥ 98% by HPLC

Solubility DMSO (>20 mg/ml)

SMILES C1C(C1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O

InChi InChI=1S/C15H15NO/c16-15-9-14(15)11-6-4-10(5-7-11)12-2-1-3-13(17)8-12/h1-8,14-15,17H,9,16H2/t14-,15+/m1/s1

InChi Key DSOJSZXQRJGBCW-CABCVRRESA-N

PubChem CID 56639570

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

OG-L002 is a potent and specific inhibitor of Lysine Specific Demethylase-1(LSD-1) (IC₅₀ of 20 nM). Displays 36- and 69-fold selectivity over MAO-B and MAO-A, respectively. It potently represses herpes simplex virus (HSV) IE gene expression, genome replication, and reactivation from latency. OG-L002 suppresses primary lytic infection of HSV in vivo in a mouse model.