ER-Hunt Red, Catalog: 9549

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ER-Tracker™ Red] [BODIPY® TR Glibenclamide; EverFluor TR Glibenclamide

PRODUCT SUMMARY

Alternate Names ER-Tracker™ Red] [BODIPY® TR Glibenclamide; EverFluor TR Glibenclamide

Appearance Blue solid

Molecular Formula C₄₄H₄₂BClF₂N₆O₇S₂

Molecular Weight 915.23

Purity ≥ 95% by HPLC

Solubility DMSO

SMILES ClC1=CC(NC(COC2=CC=C(C3=CC=C4N3[B-](F)(F)[N+]5=C(C6=CC=CS6)C=CC5=C4)C=C2)=O)=C(OC)C(C(NCCC/C=C\C(S(NC(NC7CCCCC7)=O)(=O)=O)=C)=O)=C1

InChi InChI=1S/C43H44BClF2N6O7S2/c1-28(62(57,58)51-43(56)49-31-11-6-3-7-12-31)10-5-4-8-22-48-42(55)35-24-30(45)25-36(41(35)59-2)50-40(54)27-60-34-18-14-29(15-19-34)37-20-16-32-26-33-17-21-38(39-13-9-23-61-39)53(33)44(46,47)52(32)37/h5,9-10,13-21,23-26,31H,1,3-4,6-8,11-12,22,27H2,2H3,(H,48,55)(H,50,54)(H2,49,51,56)/b10-5-

InChi Key MMJMRRFNEDFTGI-YHYXMXQVSA-N

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

DESCRIPTION

ER-Hunt Red is cell-permeable, live-cell stain that is selective for the endoplasmic reticulum (ER). Glibenclamide (glyburide) binds to the sulfonylurea receptors of ATP-sensitive K⁺ channels which are prominent on ER. lEx: 588 ± 3 nM (MeOH); lEm: 615 ± 4 nM (MeOH).