p300 Inhibitor Screening Assay, Catalog: MA-0146

IN STOCK!
US$550.00

100 wells, Fluorometric, Ex/Em = 372/465 nm

 

MA 0146 P 300 Inhibitor Screening Kit DS
PDF – 183.9 KB 104 downloads
MA 0146 SDS
PDF – 181.3 KB 98 downloads

PRODUCT SUMMARY

Catalog MA-0146

Size 100 wells

Sample Type p300 inhibitors

Method of Detection Fluorometric, Ex/Em = 372/465 nm

Assay Type Quantitative

Application A plate based fluorometric assay to screen potential p300 inhibitors in a rapid and high-throughput adaptable way.

Storage Conditions -80°C

Shipping Temperature Dry Ice

Shelf Life One year from the date of delivery

DESCRIPTION

p300, also known as KAT3B, is a histone acetyltransferase. One of the primary functions of p300 is its role in epigenetic regulation. By acetylating histones, p300 alters the structure of chromatin, promoting transcriptional activation and accessibility of genes. This process allows the cells to respond dynamically to external cues and ensure appropriate gene expression during development, tissue homeostasis, and cellular response to stress and environmental changes. Dysregulation of p300 activity has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases, making it an attractive target for therapeutic interventions. AkrivisBio’s p300 Inhibitor Screening Assay is a simple method of assessing potential p300 inhibitors in a rapid and high-throughput adaptable assay.