ML241, Catalog: 2697

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Sulphamethoxazole; Sulfisomezole; Gantanol; Sulfamethoxazol; 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide; 3-(p-Aminobenzenesulfonam

PRODUCT SUMMARY

Alternate Names N-Benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine;CID49830260

Appearance White to off-white solid

CAS # 1346528-06-0

Molecular Formula C₂₃H₂₄N₄O

Molecular Weight 372.46

Purity ≥ 98% by HPLC

Solubility DMSO

SMILES C1CCC2=C(C1)C(=NC(=N2)N3CCOC4=CC=CC=C43)NCC5=CC=CC=C5

InChi InChI=1S/C23H24N4O/c1-2-8-17(9-3-1)16-24-22-18-10-4-5-11-19(18)25-23(26-22)27-14-15-28-21-13-7-6-12-20(21)27/h1-3,6-9,12-13H,4-5,10-11,14-16H2,(H,24,25,26)

InChi Key RMZPVQQGYVSLAP-UHFFFAOYSA-N

PubChem CID 49830260

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

DESCRIPTION

ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC₅₀ = 100 nM). It blocks p97-dependent proteasome substrate with an IC₅₀ of ~ 3500 nM.