Azathioprine, Catalog: 9536

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6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine

PRODUCT SUMMARY

Alternate Names 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione

Appearance Dark blue solid

CAS # 65271-80-9

Molecular Formula C₂₂H₂₈N₄O₆

Molecular Weight 444.48

Purity ≥ 98%

Solubility DMSO (~88 mg/ml)

SMILES C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO

InChi InChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2

InChi Key KKZJGLLVHKMTCM-UHFFFAOYSA-N

PubChem CID 4212

MDL Number MFCD00242942

Handling Protect from air and light

Storage Conditions-20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

 

DESCRIPTION

Azathioprine is a purine analog that displays immunosuppressive and anti-inflammatory properties. It serves as a prodrug for 6-mercaptopurine, which alters purine processing and DNA synthesis, interfering with the proliferation of lymphocytes and other myeloid cells.