Glutathione Peroxidase Activity Assay, Catalog: MA-0137

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US$375.00

100 wells, Colorimetric, OD 450 nm

MA 0137 DS
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MA 0137 SDS
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PRODUCT SUMMARY

Catalog MA-0137

Size 100 wells

Sample Type  Tissue Extracts, Cell Lysate, Serum, Urine, Plasma, other biological fluids

Species All

Method of Detection Colorimetric, OD 450 nm

Assay Type Quantitative

Application A plate based colorimetric assay to measure Glutathione peroxidase (GPx) activity in a variety of samples with a sensitivity below 0.2 mU per well.

Sensitivity <0.2 mU/well

Storage Conditions -20°C

Shipping Temperature Gel Pack

Shelf Life One year from the date of delivery

DESCRIPTION

Glutathione peroxidase (GPx) is an essential enzyme, involved in glutathione metabolism, that helps maintain redox balance and protects against oxidative stress. GPx catalyzes the reduction of H2O2 and organic hydroperoxides, using glutathione as a co-substrate preventing accumulation of harmful reactive oxygen species within cells, which cause damage to proteins, lipids, and DNA. GPx is widely distributed throughout the body, particularly abundant in organs with high metabolic activity, (liver, kidney, lung, and red blood cells). Expression levels are modulated in response to environmental factors, including dietary selenium and oxidative stress levels. GPx deficiency is associated with pathological conditions, including neurodegenerative disease, cardiovascular disorders, cancer, and age-related macular degeneration. AkrivisBio’s  Glutathione Peroxidase Activity Assay is a simple, sensitive means of assessing GPx activity in a variety of samples with a sensitivity below 0.2 mU per well.